Bioneer, founded in 1992, is one of the world's leading suppliers of synthetic oligonucleotides (DNA and RNA). In-house production of raw materials (phosphoramidites, reagents & solvents) along with automated synthesis and purification systems result in superior quality oligos at a great price. Since Bioneer manufactures all the components of our oligos, we manage the quality control every step of the way ensuring that you receive only the highest quality product. Every Bioneer oligo is purified free of charge utilizing our unique Bio-RP cartridge purification technology. Bio-RP removes many impurities and synthesis failure products that are still present in an oligo after desalting. These impurities contribute to the OD measurement of competitor oligos that are merely desalted?and artificially inflate their yield (see below). The end result of Bioneer's Bio-RP cartridge purification is near HPLC quality purification with only full-length product. We are so confident in our oligos that we are the only company to offer a 100% guarantee that they will work for your PCR or qPCR application!
Oligo desalting vs Bio-RP Purification: Most oligos sold are merely deprotected/desalted. The process of deprotection/desalting only partially purifies the oligo and leaves behind many impurities and failure products (truncated oligos that will not amplify, and can even interfere with certain applications). These can lead to artificially inflated OD readings that increase with oligo length. Bio-RP purification removes all these contaminants and failure products, resulting in an oligo that is near HPLC purity.
All Bioneer oligos offer
- Free Bio-RP purification
- Near HPLC purity
- 100% guaranteed performance for your application, or we'll make it again